Quantifying and predicting the effect of exogenous interleukin-7 on CD4+ T cells in HIV-1 infection.

Quantifying and predicting the effect of exogenous interleukin-7 on CD4+ T cells in HIV-1 infection.

Exogenous Interleukin-7 (IL-7), in supplement to antiretroviral therapy, leads to a substantial increase of all CD4+ T cell subsets in HIV-1 infected patients. However, the quantitative contribution of the several potential mechanisms of action of IL-7 is unknown. We have performed a mathematical an...

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Bibliographic Details
Main Authors: Rodolphe Thiébaut, Julia Drylewicz, Mélanie Prague, Christine Lacabaratz, Stéphanie Beq, Ana Jarne, Thérèse Croughs, Rafick-Pierre Sekaly, Michael M Lederman, Irini Sereti, Daniel Commenges, Yves Lévy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-05-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24853554/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24853554/?tool=EBI

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