Novel Oxovanadium Complex VO(hntdtsc)(NPIP): Anticancer Activity and Mechanism of Action on HeLa Cells

Novel Oxovanadium Complex VO(hntdtsc)(NPIP): Anticancer Activity and Mechanism of Action on HeLa Cells

Oxovanadium complexes, particularly vanadyl (IV) derivatives with hybrid ligands of Schiff base and polypyridyl, have been demonstrated to possess great anticancerous therapeutic efficacy. However, most of the studies on the activity of these oxovanadium complexes have mainly focused on in vitro stu...

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Bibliographic Details
Main Authors: Yinliang Bai, Honghua Zhang, Yali Wang, Longqing Zhu, Tao Shi, Hangzhi Wei, Jiyuan Xiao, Youcheng Zhang, Zhen Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Pharmacology
Subjects:
oxovanadium (IV) complexes
VO(hntdtsc)(NPIP)
antiproliferative activity
mitochondrial-dependent apoptosis
HeLa xenograft
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.608218/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.608218/full

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