BMP-FGF signaling axis mediates Wnt-induced epidermal stratification in developing mammalian skin.

Epidermal stratification of the mammalian skin requires proliferative basal progenitors to generate intermediate cells that separate from the basal layer and are replaced by post-mitotic cells. Although Wnt signaling has been implicated in this developmental process, the mechanism underlying Wnt-med...

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Bibliographic Details
Main Authors: Xiao-Jing Zhu, YuDong Liu, Zhong-Min Dai, Xiaoyun Zhang, XueQin Yang, Yan Li, Mengsheng Qiu, Jiang Fu, Wei Hsu, YiPing Chen, Zunyi Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4199507?pdf=render