AMP-18 Targets p21 to Maintain Epithelial Homeostasis.

Dysregulated homeostasis of epithelial cells resulting in disruption of mucosal barrier function is an important pathogenic mechanism in inflammatory bowel diseases (IBD). We have characterized a novel gastric protein, Antrum Mucosal Protein (AMP)-18, that has pleiotropic properties; it is mitogenic...

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Bibliographic Details
Main Authors: Peili Chen, Yan Chun Li, F Gary Toback
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4412538?pdf=render