Doxycycline inhibits experimental cerebral malaria by reducing inflammatory immune reactions and tissue-degrading mediators.

Malaria ranks among the most important infectious diseases worldwide and affects mostly people living in tropical countries. Mechanisms involved in disease progression are still not fully understood and specific treatments that might interfere with cerebral malaria (CM) are limited. Here we show tha...

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Bibliographic Details
Main Authors: Kim E Schmidt, Janina M Kuepper, Beatrix Schumak, Judith Alferink, Andrea Hofmann, Shanshan W Howland, Laurent Rénia, Andreas Limmer, Sabine Specht, Achim Hoerauf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5811026?pdf=render