Severe, but not mild heat-shock treatment induces immunogenic cell death in cancer cells

Severe, but not mild heat-shock treatment induces immunogenic cell death in cancer cells

The mechanisms of immunogenicity underlying mild heat-shock (mHS) treatment < 42°C of tumor cells are largely attributed to the action of heat-shock proteins; however, little is known about the immunogenicity of tumor cells undergoing severe cytotoxic heat-shock treatment (sHS > 43°C). Here, w...

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Bibliographic Details
Main Authors: Irena Adkins, Lenka Sadilkova, Nada Hradilova, Jakub Tomala, Marek Kovar, Radek Spisek
Format: Article
Language:English
Published: Taylor & Francis Group 2017-05-01
Series:OncoImmunology
Subjects:
antitumor immunity
calreticulin
cancer immunotherapy
dendritic cells
heat-shock treatment
hyperthermia
immunogenic cell death
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1311433

Internet

http://dx.doi.org/10.1080/2162402X.2017.1311433

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