In vitro cytogenotoxic evaluation of sertraline

In vitro cytogenotoxic evaluation of sertraline

Sertraline (SRT) is an antidepressant agent used as a neuronal selective serotonin-reuptake inhibitor (SSRI). SRT blocks serotonin reuptake and increases serotonin stimulation of somatodendritic serotonin 1A receptor (5-HT1AR) and terminal autoreceptors in the brain. In the present study, the genoto...

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Bibliographic Details
Main Authors: Istifli Erman Salih, Çelik Rima, Hüsunet Mehmet Tahir, Çetinel Nesrin, Demirhan Osman, Ila Hasan Basri
Format: Article
Language:English
Published: Sciendo 2018-10-01
Series:Interdisciplinary Toxicology
Subjects:
sertraline
micronucleus
pbr322
peripheral blood lymphocytes
oxidative stress
cytotoxicity
Online Access:https://doi.org/10.2478/intox-2018-0015

Internet

https://doi.org/10.2478/intox-2018-0015

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