High Prevalence of Alterations in DNA Mismatch Repair Genes of Lynch Syndrome in Pediatric Patients with Adrenocortical Tumors Carrying a Germline Mutation on <i>TP53</i>

High Prevalence of Alterations in DNA Mismatch Repair Genes of Lynch Syndrome in Pediatric Patients with Adrenocortical Tumors Carrying a Germline Mutation on <i>TP53</i>

Adrenocortical cancer is a rare malignant neoplasm associated with a dismal prognosis. Identification of the molecular pathways involved in adrenal tumorigenesis is essential for a better understanding of the disease mechanism and improvement of its treatment. The aim of this study is to define the...

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Bibliographic Details
Main Authors: Vania Balderrama Brondani, Luciana Montenegro, Amanda Meneses Ferreira Lacombe, Breno Marchiori Magalhães, Mirian Yumie Nishi, Mariana Ferreira de Assis Funari, Amanda de Moraes Narcizo, Lais Cavalca Cardoso, Sheila Aparecida Coelho Siqueira, Maria Claudia Nogueira Zerbini, Francisco Tibor Denes, Ana Claudia Latronico, Berenice Bilharinho Mendonca, Madson Queiroz Almeida, Antonio Marcondes Lerario, Ibere Cauduro Soares, Maria Candida Barisson Villares Fragoso
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
adrenal tumor
dna mismatch repair
<i>tp53</i>
Online Access:https://www.mdpi.com/2072-6694/12/3/621

Internet

https://www.mdpi.com/2072-6694/12/3/621

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