Formation, Contraction, and Mechanotransduction of Myofribrils in Cardiac Development: Clues from Genetics

Congenital heart disease (CHD) is the most common birth defect in humans. It is a leading infant mortality factor worldwide, caused by defective cardiac development. Mutations in transcription factors, signalling and structural molecules have been shown to contribute to the genetic component of CHD....

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Bibliographic Details
Main Authors: Javier T. Granados-Riveron, J. David Brook
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Biochemistry Research International
Online Access:http://dx.doi.org/10.1155/2012/504906