LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing factor in Townes-Brocks Syndrome

LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing factor in Townes-Brocks Syndrome

Primary cilia are sensory organelles crucial for cell signaling during development and organ homeostasis. Cilia arise from centrosomes and their formation and function is governed by numerous factors. Through our studies on Townes-Brocks Syndrome (TBS), a rare disease linked to abnormal cilia format...

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Bibliographic Details
Main Authors: Laura Bozal-Basterra, María Gonzalez-Santamarta, Veronica Muratore, Aitor Bermejo-Arteagabeitia, Carolina Da Fonseca, Orhi Barroso-Gomila, Mikel Azkargorta, Ibon Iloro, Olatz Pampliega, Ricardo Andrade, Natalia Martín-Martín, Tess C Branon, Alice Y Ting, Jose A Rodríguez, Arkaitz Carracedo, Felix Elortza, James D Sutherland, Rosa Barrio
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-06-01
Series:eLife
Subjects:
Cilia
townes brocks syndrome
SALL1
cytoskeleton
rare disease
centrosome
Online Access:https://elifesciences.org/articles/55957

Internet

https://elifesciences.org/articles/55957

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