Compartmentalization of HIV-1 within the female genital tract is due to monotypic and low-diversity variants not distinct viral populations.

BACKGROUND:Compartmentalization of HIV-1 between the genital tract and blood was noted in half of 57 women included in 12 studies primarily using cell-free virus. To further understand differences between genital tract and blood viruses of women with chronic HIV-1 infection cell-free and cell-associ...

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Bibliographic Details
Main Authors: Marta Bull, Gerald Learn, Indira Genowati, Jennifer McKernan, Jane Hitti, David Lockhart, Kenneth Tapia, Sarah Holte, Joan Dragavon, Robert Coombs, James Mullins, Lisa Frenkel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2741601?pdf=render