Epitope predictions indicate the presence of two distinct types of epitope-antibody-reactivities determined by epitope profiling of intravenous immunoglobulins.

Epitope-antibody-reactivities (EAR) of intravenous immunoglobulins (IVIGs) determined for 75,534 peptides by microarray analysis demonstrate that roughly 9% of peptides derived from 870 different human protein sequences react with antibodies present in IVIG. Computational prediction of linear B cell...

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Bibliographic Details
Main Authors: Mitja Luštrek, Peter Lorenz, Michael Kreutzer, Zilliang Qian, Felix Steinbeck, Di Wu, Nadine Born, Bjoern Ziems, Michael Hecker, Miri Blank, Yehuda Shoenfeld, Zhiwei Cao, Michael O Glocker, Yixue Li, Georg Fuellen, Hans-Jürgen Thiesen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3823795?pdf=render