Folate pathway genes linked to mitochondrial biogenesis and respiration are associated with outcome of patients with stage III colorectal cancer
5-fluorouracil in combination with the folate leucovorin is the cornerstone in treatment of colorectal cancer. Transport of leucovorin into cells, and subsequent metabolic action, require expression of several genes. The aim was to analyze if tumoral expression of genes putatively involved in leucov...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
IOS Press
2019-06-01
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| Series: | Tumor Biology |
| Online Access: | https://doi.org/10.1177/1010428319846231 |