Antimalarial antibody repertoire defined by plasma IG proteomics and single B cell IG sequencing

Antimalarial antibody repertoire defined by plasma IG proteomics and single B cell IG sequencing

Plasma antimalarial Ab can mediate antiparasite immunity but has not previously been characterized at the molecular level. Here, we develop an innovative strategy to characterize humoral responses by integrating profiles of plasma immunoglobulins (IGs) or Abs with those expressed on B cells as part...

Full description

Bibliographic Details
Main Authors: Camila H. Coelho, Steven T. Nadakal, Patricia Gonzales Hurtado, Robert Morrison, Jacob D. Galson, Jillian Neal, Yimin Wu, C. Richter King, Virginia Price, Kazutoyo Miura, Sharon Wong-Madden, Justin Yai Alamou Doritchamou, David L. Narum, Nicholas J. MacDonald, Maryonne Snow-Smith, Marissa Vignali, Justin J. Taylor, Marie-Paule Lefranc, Johannes Trück, Carole A. Long, Issaka Sagara, Michal Fried, Patrick E. Duffy
Format: Article
Language:English
Published: American Society for Clinical investigation 2020-11-01
Series:JCI Insight
Subjects:
Immunology
Vaccines
Online Access:https://doi.org/10.1172/jci.insight.143471

Internet

https://doi.org/10.1172/jci.insight.143471

Similar Items