The Ultrastructural Analysis of Human Colorectal Cancer Stem Cell-Derived Spheroids and Their Mouse Xenograft Shows That the Same Cells Types Have Different Ratios

The Ultrastructural Analysis of Human Colorectal Cancer Stem Cell-Derived Spheroids and Their Mouse Xenograft Shows That the Same Cells Types Have Different Ratios

Spheroids from primary colorectal cancer cells and their mice xenografts have emerged as useful preclinical models for cancer research as they replicate tumor features more faithfully as compared to cell lines. While 3D models provide a reliable system for drug discovery and testing, their structura...

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Bibliographic Details
Main Authors: Michela Relucenti, Federica Francescangeli, Maria Laura De Angelis, Vito D’Andrea, Selenia Miglietta, Emanuela Pilozzi, Xiaobo Li, Alessandra Boe, Rui Chen, Ann Zeuner, Giuseppe Familiari
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biology
Subjects:
spheroid
xenotransplant
cancer stem cell
colorectal cancer
electron microscopy
flow cytometry
Online Access:https://www.mdpi.com/2079-7737/10/9/929

Internet

https://www.mdpi.com/2079-7737/10/9/929

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