Excessive cytokine response to rapid proliferation of highly pathogenic avian influenza viruses leads to fatal systemic capillary leakage in chickens.

Excessive cytokine response to rapid proliferation of highly pathogenic avian influenza viruses leads to fatal systemic capillary leakage in chickens.

Highly pathogenic avian influenza viruses (HPAIVs) cause lethal infection in chickens. Severe cases of HPAIV infections have been also reported in mammals, including humans. In both mammals and birds, the relationship between host cytokine response to the infection with HPAIVs and lethal outcome has...

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Bibliographic Details
Main Authors: Saya Kuribayashi, Yoshihiro Sakoda, Takeshi Kawasaki, Tomohisa Tanaka, Naoki Yamamoto, Masatoshi Okamatsu, Norikazu Isoda, Yoshimi Tsuda, Yuji Sunden, Takashi Umemura, Noriko Nakajima, Hideki Hasegawa, Hiroshi Kida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3706397?pdf=render

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http://europepmc.org/articles/PMC3706397?pdf=render

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