The Roles of Histone Demethylase Jmjd3 in Osteoblast Differentiation and Apoptosis

Posttranslational modifications including histone methylation regulate gene transcription through directly affecting the structure of chromatin. Trimethylation of histone 3 lysine 27 (H3K27me3) is observed at the promoters of a wide variety of important genes, especially for mammalian development, a...

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Bibliographic Details
Main Authors: Di Yang, Bo Yu, Haiyan Sun, Lihong Qiu
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:http://www.mdpi.com/2077-0383/6/3/24