IGF2R Genetic Variants, Circulating IGF2 Concentrations and Colon Cancer Risk in African Americans and Whites

IGF2R Genetic Variants, Circulating IGF2 Concentrations and Colon Cancer Risk in African Americans and Whites

The Mannose 6 Phosphate/Insulin-like Growth Factor Receptor-2 (IGF2R) encodes a type-1 membrane protein that modulates availability of the potent mitogen, IGF2. We evaluated the associations between IGF2R non-synonymous genetic variants (c.5002G>A, Gly1619Arg(rs629849), and c.901C>G, Leu252Val...

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Bibliographic Details
Main Authors: Cathrine Hoyo, Susan K. Murphy, Joellen M. Schildkraut, Adriana C. Vidal, David Skaar, Robert C. Millikan, Joseph Galanko, Robert S. Sandler, Randy Jirtle, Temitope Keku
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.3233/DMA-2011-0865

Internet

http://dx.doi.org/10.3233/DMA-2011-0865

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