Salmonella Typhimurium type III secretion effectors stimulate innate immune responses in cultured epithelial cells.

Recognition of conserved bacterial products by innate immune receptors leads to inflammatory responses that control pathogen spread but that can also result in pathology. Intestinal epithelial cells are exposed to bacterial products and therefore must prevent signaling through innate immune receptor...

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Bibliographic Details
Main Authors: Vincent M Bruno, Sebastian Hannemann, María Lara-Tejero, Richard A Flavell, Steven H Kleinstein, Jorge E Galán
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2714975?pdf=render