Mouse T cell priming is enhanced by maturation-dependent stiffening of the dendritic cell cortex
T cell activation by dendritic cells (DCs) involves forces exerted by the T cell actin cytoskeleton, which are opposed by the cortical cytoskeleton of the interacting antigen-presenting cell. During an immune response, DCs undergo a maturation process that optimizes their ability to efficiently prim...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-07-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/55995 |