Suppression of Host p53 Is Critical for Plasmodium Liver-Stage Infection

Plasmodium parasites infect the liver and replicate inside hepatocytes before they invade erythrocytes and trigger clinical malaria. Analysis of host signaling pathways affected by liver-stage infection could provide critical insights into host–pathogen interactions and reveal targets for intervent...

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Bibliographic Details
Main Authors: Alexis Kaushansky, Albert S. Ye, Laura S. Austin, Sebastian A. Mikolajczak, Ashley M. Vaughan, Nelly Camargo, Peter G. Metzger, Alyse N. Douglass, Gavin MacBeath, Stefan H.I. Kappe
Format: Article
Language:English
Published: Elsevier 2013-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713000697