LAT1 Is a Central Transporter of Essential Amino Acids in Human Umbilical Vein Endothelial Cells

Endothelial cell proliferation supporting angiogenesis requires sufficient nutrient supply because of facilitated intracellular metabolism. However, little is known about the mechanism for the promotion of nutrient incorporation in proliferating endothelial cells. Here we show that L-type amino acid...

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Bibliographic Details
Main Authors: Keitaro Hayashi, Promsuk Jutabha, Takao Kamai, Hitoshi Endou, Naohiko Anzai
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319301744