A Single-use Strategy to Enable Manufacturing of Affordable Biologics

A Single-use Strategy to Enable Manufacturing of Affordable Biologics

The current processing paradigm of large manufacturing facilities dedicated to single product production is no longer an effective approach for best manufacturing practices. Increasing competition for new indications and the launch of biosimilars for the monoclonal antibody market have put pressure...

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Bibliographic Details
Main Authors: Renaud Jacquemart, Melissa Vandersluis, Mochao Zhao, Karan Sukhija, Navneet Sidhu, Jim Stout
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Flexible, single-use facilities
Continuous bioprocessing
Antibody manufacturing paradigms
Process economics
Affinity membrane chromatography
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037016300289

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http://www.sciencedirect.com/science/article/pii/S2001037016300289

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