Food intake regulation during pregnancy and lactation in mice with reduced activity of the melanocortin system

Hypothalamic melanortin receptor (MCR) activation inhibits appetite. Neuropeptide Y (NPY) and Agouti Related Protein (AgRP) are coexpressed in some hypothalamic neurons and stimulate feeding, NPY via inhibition of MCR-expressing neurons, and AgRP via MCR4 antagonism. Mutation yellow at the mouse ago...

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Bibliographic Details
Main Authors: E. N. Makarova, I. V. Romanova, N. M. Bazhan
Format: Article
Language:English
Published: Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences 2016-05-01
Series:Vavilovskij Žurnal Genetiki i Selekcii
Subjects:
npy
Online Access:https://vavilov.elpub.ru/jour/article/view/578