OPTIMIZATION OF SOLID-PHASE SYNTHESIS OF POLYAMIDE NUCLEIC ACID MIMETICS WITH APPLICATION OF MALDI-TOF MASS-SPECTROMETRY

The solid-phase synthesis of a tetrameric model sequence of polyamide nucleic acid mimetics (PANAM) incorporating terminal chiral and charged unit was performed. As a result during the synthesis and cleavage from the resin the tendency of PANAM with the N-terminal negatively charged monomer to cycli...

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Bibliographic Details
Main Authors: M. V. Shirayeva, Yu. G. Kirillova, E. D. Nikol’Skaya, D. I. Prokhorov, I. P. Smirnov, G. E. Pozmogova
Format: Article
Language:Russian
Published: MIREA - Russian Technological University 2013-02-01
Series:Тонкие химические технологии
Subjects:
Online Access:https://www.finechem-mirea.ru/jour/article/view/659