HDAC3 and HDAC8 are required for cilia assembly and elongation

Cilia are extended from mother centrioles in quiescent G0/G1 cells and retracted in dividing cells. Diverse post-translational modifications play roles in the assembly and disassembly of the cilium. Here, we examined class I histone deacetylases (HDACs) as positive regulators of cilia assembly in se...

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Bibliographic Details
Main Authors: Seon-ah Park, Hyunjeong Yoo, Jae Hong Seol, Kunsoo Rhee
Format: Article
Language:English
Published: The Company of Biologists 2019-08-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/8/8/bio043828