Investigation of Metal-Organic Framework-5 (MOF-5) as an Antitumor Drug Oridonin Sustained Release Carrier

Investigation of Metal-Organic Framework-5 (MOF-5) as an Antitumor Drug Oridonin Sustained Release Carrier

Oridonin (ORI) is a natural active ingredient with strong anticancer activity. But its clinical use is restricted due to its poor water solubility, short half-life, and low bioavailability. The aim of this study is to utilize the metal organic framework material MOF-5 to load ORI in order to improve...

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Bibliographic Details
Main Authors: Gongsen Chen, Juyuan Luo, Mengru Cai, Liuying Qin, Yibo Wang, Lili Gao, Pingqing Huang, Yingchao Yu, Yangming Ding, Xiaoxv Dong, Xingbin Yin, Jian Ni
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Molecules
Subjects:
MOF-5
Oridonin
Antitumor
HepG2 cells
sustained release
Online Access:https://www.mdpi.com/1420-3049/24/18/3369

Internet

https://www.mdpi.com/1420-3049/24/18/3369

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