Exploring the potential of 3D Zernike descriptors and SVM for protein–protein interface prediction

Abstract Background The correct determination of protein–protein interaction interfaces is important for understanding disease mechanisms and for rational drug design. To date, several computational methods for the prediction of protein interfaces have been developed, but the interface prediction pr...

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Bibliographic Details
Main Authors: Sebastian Daberdaku, Carlo Ferrari
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Bioinformatics
Subjects:
SVM
Online Access:http://link.springer.com/article/10.1186/s12859-018-2043-3