Identification of deleterious and regulatory genomic variations in known asthma loci

Abstract Background Candidate gene and genome-wide association studies have identified hundreds of asthma risk loci. The majority of associated variants, however, are not known to have any biological function and are believed to represent markers rather than true causative mutations. We hypothesized...

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Bibliographic Details
Main Authors: Matthew D. C. Neville, Jihoon Choi, Jonathan Lieberman, Qing Ling Duan
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Respiratory Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12931-018-0953-2