Upregulation of MUC5AC by VEGF in human primary bronchial epithelial cells: implications for asthma
Abstract Background Airway mucus hypersecretion is an important pathophysiological feature in asthma. Mucins are glycoproteins that are mainly responsible for the viscoelastic property of mucus, and MUC5AC is a major mucin glycoprotein that is overproduced in asthma. Vascular endothelial growth fact...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-12-01
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Series: | Respiratory Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12931-019-1245-1 |