Histamine H3 receptor density is negatively correlated with neural activity related to working memory in humans

Histamine H3 receptor density is negatively correlated with neural activity related to working memory in humans

Abstract Background The histamine H3 receptor is regarded as a drug target for cognitive impairments in psychiatric disorders. H3 receptors are expressed in neocortical areas, including the prefrontal cortex, the key region of cognitive functions such as working memory. However, the role of prefront...

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Bibliographic Details
Main Authors: Takehito Ito, Yasuyuki Kimura, Chie Seki, Masanori Ichise, Keita Yokokawa, Kazunori Kawamura, Hidehiko Takahashi, Makoto Higuchi, Ming-Rong Zhang, Tetsuya Suhara, Makiko Yamada
Format: Article
Language:English
Published: SpringerOpen 2018-06-01
Series:EJNMMI Research
Subjects:
Histamine H3 receptor
Working memory
PET
fMRI
Online Access:http://link.springer.com/article/10.1186/s13550-018-0406-4

Internet

http://link.springer.com/article/10.1186/s13550-018-0406-4

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