HiNO: an approach for inferring hierarchical organization from regulatory networks.

BACKGROUND: Gene expression as governed by the interplay of the components of regulatory networks is indeed one of the most complex fundamental processes in biological systems. Although several methods have been published to unravel the hierarchical structure of regulatory networks, weaknesses such...

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Bibliographic Details
Main Authors: Mara L Hartsperger, Robert Strache, Volker Stümpflen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2973965?pdf=render