Algorithms for efficiently collapsing reads with Unique Molecular Identifiers
Background Unique Molecular Identifiers (UMI) are used in many experiments to find and remove PCR duplicates. There are many tools for solving the problem of deduplicating reads based on their finding reads with the same alignment coordinates and UMIs. However, many tools either cannot handle substi...
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| Format: | Article |
| Language: | English |
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PeerJ Inc.
2019-12-01
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| Series: | PeerJ |
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| Online Access: | https://peerj.com/articles/8275.pdf |