Increased ERCC1 expression is linked to chromosomal aberrations and adverse tumor biology in prostate cancer

Increased ERCC1 expression is linked to chromosomal aberrations and adverse tumor biology in prostate cancer

Abstract Background Animal model experiments have suggested a role of the DNA repair protein ERCC1 (Excision Repair Cross-Complementation Group 1) in prostate cancer progression. Methods To better understand the impact of ERCC1 protein expression in human prostate cancer, a preexisting tissue microa...

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Bibliographic Details
Main Authors: Frank Jacobsen, Billurvan Taskin, Nathaniel Melling, Charlotte Sauer, Corinna Wittmer, Claudia Hube-Magg, Martina Kluth, Ronald Simon, Dirk Pehrke, Burkhard Beyer, Thomas Steuber, Imke Thederan, Guido Sauter, Thorsten Schlomm, Waldemar Wilczak, Katharina Möller, Sören A. Weidemann, Susanne Burdak-Rothkamm
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Cancer
Subjects:
ERCC1
DNA repair
Prostate cancer
Prognosis
Online Access:http://link.springer.com/article/10.1186/s12885-017-3489-9

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http://link.springer.com/article/10.1186/s12885-017-3489-9

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