α-Glucosidase inhibitory effect of rhinacanthins-rich extract from Rhinacanthus nasutus leaf and synergistic effect in combination with acarbose

α-Glucosidase inhibitory effect of rhinacanthins-rich extract from Rhinacanthus nasutus leaf and synergistic effect in combination with acarbose

Rhinacanthins-rich extract (RRE) from Rhinacanthus nasutus leaf and its marker compounds namely rhinacanthin-C, rhinacanthin-D and rhinacanthin-N were evaluated for α-glucosidase inhibitory activity. RRE (IC50 value of 25.0 µg/mL) exhibited α-glucosidase inhibitory activity almost equivalent to that...

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Bibliographic Details
Main Authors: Muhammad Ajmal Shah, Ruqaiya Khalil, Zaheer Ul-Haq, Pharkphoom Panichayupakaranant
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Journal of Functional Foods
Subjects:
α-Glucosidase
Diabetes mellitus
Rhinacanthus nasutus
Rhinacanthins-rich extract
Rhinacanthin-C
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617304085

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http://www.sciencedirect.com/science/article/pii/S1756464617304085

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