Growth differentiation factor 15 (GDF-15) plasma levels increase during bleomycin- and cisplatin-based treatment of testicular cancer patients and relate to endothelial damage.

Growth differentiation factor 15 (GDF-15) plasma levels increase during bleomycin- and cisplatin-based treatment of testicular cancer patients and relate to endothelial damage.

INTRODUCTION:Chemotherapy-related endothelial damage contributes to the early development of cardiovascular morbidity in testicular cancer patients. We aimed to identify relevant mechanisms of and search for candidate biomarkers for this endothelial damage. METHODS:Human micro-vascular endothelial c...

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Bibliographic Details
Main Authors: Renske Altena, Rudolf S N Fehrmann, Hink Boer, Elisabeth G E de Vries, Coby Meijer, Jourik A Gietema
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4295859?pdf=render

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http://europepmc.org/articles/PMC4295859?pdf=render

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