Adolescent but not adult-born neurons are critical for susceptibility to chronic social defeat

Recent evidence implicates adult hippocampal neurogenesis in regulating behavioral and physiologic responses to stress. Hippocampal neurogenesis occurs across the lifespan, however the rate of cell birth is up to 300% higher in adolescent mice compared to adults. Adolescence is a sensitive period in...

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Bibliographic Details
Main Authors: Greer S Kirshenbaum, Sophie Rose Lieberman, Tamara J Briner, Eduardo David Leonardo, Alex eDranovsky
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00289/full