Overexpression of Galectin-9 in Islets Prolongs Grafts Survival via Downregulation of Th1 Responses
The differential activation of T helper (Th) cells and production of cytokines contribute to graft rejection or tolerance. In general, the Th1-type cytokines and cytotoxic T-cells are detected consistently in a host who is undergoing rejection, whereas Th2 responses are linked to a tolerance conditi...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2013-11-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.3727/096368912X657891 |