Model Based Analysis of Clonal Developments Allows for Early Detection of Monoclonal Conversion and Leukemia.

The availability of several methods to unambiguously mark individual cells has strongly fostered the understanding of clonal developments in hematopoiesis and other stem cell driven regenerative tissues. While cellular barcoding is the method of choice for experimental studies, patients that underwe...

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Bibliographic Details
Main Authors: Christoph Baldow, Lars Thielecke, Ingmar Glauche
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5072636?pdf=render