Sleep pattern and learning in knockdown mice with reduced cholinergic neurotransmission

Sleep pattern and learning in knockdown mice with reduced cholinergic neurotransmission

Impaired cholinergic neurotransmission can affect memory formation and influence sleep-wake cycles (SWC). In the present study, we describe the SWC in mice with a deficient vesicular acetylcholine transporter (VAChT) system, previously characterized as presenting reduced acetylcholine release and co...

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Bibliographic Details
Main Authors: C.M. Queiroz, P.A. Tiba, K.M. Moreira, P.A.M. Guidine, G.H.S. Rezende, M.F.D. Moraes, M.A.M. Prado, V.F. Prado, S. Tufik, L.E. Mello
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2013-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Sleep-wake cycle
Intermediate sleep
Acetylcholine
Contextual fear conditioning
Memory
Neurodegenerative disorders
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001000844&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001000844&lng=en&tlng=en

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