Structural Insights into AQP2 Targeting to Multivesicular Bodies

Structural Insights into AQP2 Targeting to Multivesicular Bodies

Vasopressin-dependent trafficking of AQP2 in the renal collecting duct is crucial for the regulation of water homeostasis. This process involves the targeting of AQP2 to the apical membrane during dehydration as well as its removal when hydration levels have been restored. The latter involves AQP2 e...

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Bibliographic Details
Main Authors: Jennifer Virginia Roche, Veronika Nesverova, Caroline Olsson, Peter MT Deen, Susanna Törnroth-Horsefield
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
aquaporin 2
water channel
multivesicular bodies
lysosomal trafficking regulator-interacting protein 5
trafficking
protein sorting
Online Access:https://www.mdpi.com/1422-0067/20/21/5351

Internet

https://www.mdpi.com/1422-0067/20/21/5351

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