Plasma-Derived microRNAs Are Influenced by Acute and Chronic Exercise in Patients With Heart Failure With Reduced Ejection Fraction

Background: Exercise training improves VO2peak in heart failure with reduced ejection fraction (HFrEF), but the effect is highly variable as it is dependent on peripheral adaptations. We evaluated changes in plasma-derived miRNAs by acute and chronic exercise to investigate whether these can mechani...

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Bibliographic Details
Main Authors: Isabel Witvrouwen, Andreas B. Gevaert, Nadine Possemiers, Bert Ectors, Tibor Stoop, Inge Goovaerts, Evi Boeren, Wendy Hens, Paul J. Beckers, Anne Vorlat, Hein Heidbuchel, Amaryllis H. Van Craenenbroeck, Emeline M. Van Craenenbroeck
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Physiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.736494/full