Progenitor expansion in <it>apc </it>mutants is mediated by Jak/Stat signaling
<p>Abstract</p> <p>Background</p> <p>Mutations in <it>APC</it>, a negative regulator of the Wnt/ß-catenin pathway, can cause cancer as well as profound developmental defects. In both cases, affected cells adopt a proliferative progenitor state and fail to di...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-12-01
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| Series: | BMC Developmental Biology |
| Subjects: | |
| Online Access: | http://www.biomedcentral.com/1471-213X/11/73 |