Pharmacological Characterization of Toludesvenlafaxine as a Triple Reuptake Inhibitor

Toludesvenlafaxine hydrochloride dihydrate is a novel chemical entity and a potential triple monoamine reuptake inhibitor. This study characterized the in vitro triple reuptake inhibition activity, antidepressant-like activity in animals, and pharmacokinetic profiles in rats of toludesvenlafaxine. B...

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Bibliographic Details
Main Authors: Haibo Zhu, Wenyan Wang, Chunjie Sha, Wei Guo, Chunmei Li, Fengjuan Zhao, Hongbo Wang, Wanglin Jiang, Jingwei Tian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.741794/full