Correlation of polyamines, acrolein-conjugated lysine and polyamine metabolic enzyme levels with age in human liver

The polyamines spermidine, spermine and putrescine are essential for normal cellular functions. The contents of polyamines in tissue decreased in aged mice compared to young mice. In this study, the polyamine contents and their metabolic byproduct acrolein-conjugated lysine (Nε-(3-formyl-3,4-dehydro...

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Bibliographic Details
Main Authors: Takeshi Uemura, Yoshihisa Akasaka, Hiroshi Ikegaya
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020318740