Helicobacter pylori with East Asian-type cagPAI genes is more virulent than strains with Western-type in some cagPAI genes

Abstract The severity of Helicobacter pylori-related disease is correlated with the presence and integrity of a cag pathogenicity island (cagPAI). cagPAI genotype may have a modifying effect on the pathogenic potential of the infecting strain. After analyzing the sequences of cagPAI genes, some stra...

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Bibliographic Details
Main Authors: Xiao-yan Yuan, Jin-Jun Yan, Ya-chao Yang, Chun-mei Wu, Yan Hu, Jian-li Geng
Format: Article
Language:English
Published: Sociedade Brasileira de Microbiologia
Series:Brazilian Journal of Microbiology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822017000200218&lng=en&tlng=en