Abnormalities in oxygen sensing define early and late onset preeclampsia as distinct pathologies.
The pathogenesis of preeclampsia, a serious pregnancy disorder, is still elusive and its treatment empirical. Hypoxia Inducible Factor-1 (HIF-1) is crucial for placental development and early detection of aberrant regulatory mechanisms of HIF-1 could impact on the diagnosis and management of preecla...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-10-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2953500?pdf=render |