Abnormalities in oxygen sensing define early and late onset preeclampsia as distinct pathologies.
The pathogenesis of preeclampsia, a serious pregnancy disorder, is still elusive and its treatment empirical. Hypoxia Inducible Factor-1 (HIF-1) is crucial for placental development and early detection of aberrant regulatory mechanisms of HIF-1 could impact on the diagnosis and management of preecla...
Main Authors: | Alessandro Rolfo, Ariel Many, Antonella Racano, Reshef Tal, Andrea Tagliaferro, Francesca Ietta, Jinxia Wang, Martin Post, Isabella Caniggia |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-10-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2953500?pdf=render |
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