Aspirin treatment of mice infected with Trypanosoma cruzi and implications for the pathogenesis of Chagas disease.

Chagas disease, caused by infection with Trypanosoma cruzi, is an important cause of cardiovascular disease. It is increasingly clear that parasite-derived prostaglandins potently modulate host response and disease progression. Here, we report that treatment of experimental T. cruzi infection (Brazi...

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Bibliographic Details
Main Authors: Shankar Mukherjee, Fabiana S Machado, Huang Huang, Helieh S Oz, Linda A Jelicks, Cibele M Prado, Wade Koba, Eugene J Fine, Dazhi Zhao, Stephen M Factor, J Elias Collado, Louis M Weiss, Herbert B Tanowitz, Anthony W Ashton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3039660?pdf=render