Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes.

Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes.

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To get beyond the "low-hanging fruits" so far identified by genome-wide association (GWA) studies, new methods must be developed in order to discover the numerous remaining genes that estimates of heritability indicate should be contributing to complex human phenotypes, such as obesity. He...

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Bibliographic Details
Main Authors: Jussi Naukkarinen, Ida Surakka, Kirsi H Pietiläinen, Aila Rissanen, Veikko Salomaa, Samuli Ripatti, Hannele Yki-Järvinen, Cornelia M van Duijn, H-Erich Wichmann, Jaakko Kaprio, Marja-Riitta Taskinen, Leena Peltonen, ENGAGE Consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2880558?pdf=render

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http://europepmc.org/articles/PMC2880558?pdf=render

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